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Supplements: Natural or Synthetic?

small glass bowl of supplements with herbs

There’s no doubt that vitamins and minerals are important to maintain both short- and long-term health. But does the source of the nutrients matter? You’ll find a lot of criticism about synthetic vitamins from various nutritionists and natural vitamin companies arguing that our bodies do not know how to digest these supplements.

But is this true? Or is this another marketing ploy to make you buy the more expensive, lesser processed vitamins?

What is a natural vitamin? 

Similar to ‘natural’ foods, the natural vitamin label is not clearly defined and can be very misleading. A natural vitamin can be made from a component directly from the earth or it can be ‘naturally made’ in your body through digestion. It can also be a product, like vitamin B, that begins with natural fermentation but is additionally processed.

All-natural vitamins are created directly from plant material. However, since supplements obviously don’t grow on trees, the only completely natural vitamin is something that comes directly from your food or made within our bodies.

To remove any vitamin from its natural source is a tricky and expensive process that also reduces the potency of the particular nutrient. So you have to ‘synthesize’ the vitamin anyway to reach full potency.

In our exploration of synthetic vitamins, we came across some great research from Willner Chemists, a nutritional pharmacy located in New York City. These pharmaceutical researchers explain the purpose of synthetic vitamins very clearly.

According to Dr. Donald Goldberg, R.Ph and Dr. Arnold Gitomer, R.Ph.:

“Yes, vitamins and minerals occur naturally in food. But the quantities are very small…

To get 500 milligrams of vitamin C and 10 milligrams of the various B vitamins from natural sources would require a tablet the size of a football.

With a few exceptions—such as vitamin E, natural beta-carotene, and vitamin B12—all of the vitamins used in dietary supplements are synthetic…these synthetic vitamins are identical to their natural counterparts. To get high potencies of vitamins and minerals in a dietary supplement, synthetic or highly processed vitamins, and minerals must be used. You cannot have it both ways.”

What is a synthetic vitamin?

Synthetic nutrients are replicated in the lab to support their specific cellular structure and function. Because the vitamin is specifically isolated, the lab can easily control the purity and quality.

The only exception is vitamin E, a crucial antioxidant. Vitamin C combined with vitamin E may increase the photoprotection of your skin more than vitamin E by itself.

Naturally-occurring vitamin E found in spinach, nuts, and oils, contains eight molecules called tocopherols and tocotrienols. A synthetic vitamin can only capture one tocopherol.

So here’s a helpful hint: Look for a ‘d’ label before the word alpha-tocopherol rather than a ‘dl’ label which means it is synthetic. This “dl” tip also works for determining the source for other vitamins, as well.

Aside from Vitamin E, there is no difference between natural and synthetic vitamins. In fact, 95% of vitamins on the market are synthetic, because it’s actually very difficult to put natural vitamins into most supplements.

Are natural vitamins healthier for our body?

“All-natural” vitamin companies often tout their process of creating “natural” vitamins as being better for your health. But one thing is true: natural supplements are typically far more taxing on your budget than synthetic supplements.

Natural vitamin companies often claim that your body will not know how to process vitamins that have been created synthetically. The main criticism is that synthetic vitamins are ‘isolated’ and since they are not working in conjunction with other vitamins, enzymes and minerals the human body does not recognize the isolated ones.

Contrary to this argument, reputable labs will actually create a ‘human stomach’ to test how the vitamins break down and release the nutrients. They copy the temperature, average acidity, and how the stomach churns during digestion. Of course, there are individual variants such as your gut microbiota, age, and overall health profile that will affect how your own body digests and absorbs the vitamin.

Are synthetic vitamins filled with unhealthy additives?

Companies producing all-natural vitamins indicate their products are free of artificial flavorings and colorings, chemical preservatives and other synthetic ingredients. Natural companies use only natural flavoring agents such as herbal extracts, lemon, and vanilla with no chemical dyes.

Synthetic supplements are criticized for using binders to hold tablets together, or fillers such as cellulose or magnesium stearate for encapsulation. However, not all of these processing ingredients are bad.

For instance, cellulose is a carbohydrate found in plants; if you eat lettuce or spinach, you are also eating cellulose.

Magnesium stearate is used to make sure the ingredients blend together proportionally and easily slides through the manufacturing process. It is basically a combination of stearic acid (a saturated fat found in beef, cocoa butter, and coconut oil) and magnesium salt. Both of these additives are generally regarded as safe by the FDA.

Regulation of vitamin products

The FDA and WHO do not distinguish between all natural and synthetic vitamins. In fact, dietary supplements are not regulated by the FDA the same way drugs are. This is due to the fact that you can make therapeutic claims for drugs, which you cannot do for dietary supplements.

In terms of vitamins, FDA regulations are responsible for the purity, potency, and safety of dietary supplements being created. They concur that the molecular structures of nutrients are well known and the body cannot tell if a nutrient came from a lab or a plant.

The question is not whether a vitamin is synthetic or natural, but was it made by a reputable manufacturer that uses FDA Good Manufacturing processes and uses a third-party company for their testing.

Be sure your vitamin supplements are tested for toxicity and contaminants, are properly labeled, and will break down in your body in the appropriate amount of time.

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Inflation’s Effect on Family Budgets

In Mintel’s latest comprehensive report, Michele Scott, Associate Director of US Research for Food and Drink at Mintel, explores the evolving landscape of family meal planning and the challenges of inflation, budgets, and getting what consumers want.

This summary highlights the key findings and insights from the report, along with some takeaways and future outlook for consumers.

Key Findings and Insights

The primary focus of this report is on the balance between nutrition, convenience, and the associated stressors faced by families in the U.S. Here’s what today’s consumers prioritize:

Nutrition and Convenience

Nutrition is the most important attribute for families when it comes to feeding their children, with 84% of consumers agreeing on its significance. However, while nutrition is essential, families are not willing to pay extra for it.

Instead, ease and speed of meal preparation and cleanup are the attributes families are most willing to pay a premium for. This indicates a significant opportunity for brands to simplify the family meal experience.

Source for chart: Mintel

Economic Pressures and Inflation

The report highlights the ongoing impact of economic pressures on families, particularly inflation and the cost of living. Inflation has remained sticky, especially concerning food, making feeding the family a persistent challenge.

Despite improvements in the broader economy, food prices have stayed high, causing stress for families. With food being a non-negotiable purchase, grocery shopping has become particularly stressful, emphasizing the need for affordable convenience solutions.

Smaller Family Sizes and Budget Constraints

Families today are getting smaller, and budgets are tighter. This trend complicates the concept of “family size,” as bulk or multi-serving products need to be reframed in terms of value and convenience. Products that assist with meal planning and preparation resonate broadly, as they help manage both time and financial constraints.

Smaller family sizes create a need for products that offer flexible portion sizes or can be easily repurposed as leftovers, reducing food waste and maximizing value.

Frozen Food Popularity

The increasing popularity of frozen foods is a key trend identified in the report. Frozen meals reduce the pressure of expiration dates, making them a practical choice for families looking to balance convenience and budget. These products provide a solution that is both cost-effective and reduces food waste.

Struggling families, often working long hours to make ends meet, particularly benefit from the convenience and affordability of frozen foods. This trend indicates a shift towards products that can offer both ease of use and economic value.

Innovations in Family Meal Solutions

Bulk and Flexible Portion Products

Brands are introducing bulk proteins and flexible portion products to cater to families of all sizes. These products allow consumers to use exactly what they need, reducing waste and making meal planning more efficient. For example, pre-cooked bulk proteins can be used as needed, providing a quick solution for both small and large families.

Ready-to-Eat and Frozen Meals

Ready-to-eat (RTE) and frozen meals are increasingly popular, offering total meal solutions that mimic foodservice quality without the high price. Brands are focusing on quality and convenience, ensuring these meals are nutritious, quick to prepare, and cater to diverse tastes.

Private Label Innovations

Private labels are stepping up with innovative side dishes and snacks, often at lower prices than national brands. These products range from casual family dinners to special occasions, providing consumers with high-quality, convenient options. Examples include Target’s savory sides and Aldi’s grain and gluten-free snacks, which cater to dietary restrictions and preferences.

Kid-Friendly Meal Solutions

Products designed for easy preparation by children are gaining traction. Brands are creating tiered approaches, from simple heat-and-eat options to meals with minimal ingredients and safe cooking instructions. These solutions empower kids to help in the kitchen, reducing the burden on parents.

Single-Serve and Portion-Controlled Meals

Brands are breaking stereotypes of TV dinners with single-serve meals that offer high-quality, nutritious options. These meals cater to individual needs, whether due to scheduling conflicts or varying family member preferences.

Enhanced Meal Planning Tools

Brands and retailers are collaborating to offer comprehensive meal planning tools. These tools include pre-made shopping lists, meal plans, and product suggestions that simplify the planning process and ensure balanced, nutritious meals.

Takeaways from Savvy Consumers

Simplify Meal Planning

  • Look for products that offer meal planning assistance, such as pre-made shopping lists or meal kits, to save time and reduce stress

Embrace Convenience

  • For busy families, ready-to-eat and frozen meals provide quick, nutritious solutions without the prep

Value in Versatility

  • Smaller families benefit from products offering flexible portion sizes or repurposed as leftovers to reduce food waste and maximize value

Nutritional Balance

  • Families seek products balancing nutrition and ease of preparation to ensure healthy meals without added stress

Smart Shopping

  • Seeking out products that clearly communicate nutritional benefits and prep time make meal choices easier and faster

Looking Ahead

The future of family meal planning will likely see a continued emphasis on convenience as economic pressures and time constraints persist. Brands that can offer products that reduce meal-time stress will be in high demand. Smaller family sizes will drive the need for more flexible portion sizes and innovative solutions that cater to diverse family structures.

Are consumers willing to pay for sustainability?

As sustainability becomes an increasingly important issue, families are showing a bit more willingness to pay more for sustainable products.

However, the report highlights that convenience and nutrition are top priorities, with a significant portion of consumers also valuing sustainability in their purchasing decisions, it is not the top need in these economic times. This willingness is often balanced against budget constraints and the overall value perceived in the product.

As economic conditions fluctuate, the attributes families prioritize may shift. In times of economic prosperity, convenience products may become even more valuable. Conversely, during economic downturns, families may prioritize cost-saving measures, making affordable convenience solutions critical.

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Too much protein or not enough?

Today’s high-protein diet takes many forms. From the Atkins diet to the paleo diet and even some versions of the keto diet, protein is often touted as the miracle macronutrient. You’ve probably seen countless protein shakes, bars, and protein-fortified foods lining the shelves of your local grocery store.

How much protein do we need?

But first, let’s clear the air…protein is a critical component of our diet. It’s involved in virtually every biochemical function in our body, from building and repairing tissues to producing enzymes and hormones.

So, how much protein do our bodies need to conduct these essential tasks? To get a better idea, we spoke with Registered Dietitian, Jamie Kesmodel, MS, RDN, who works at Culina Health, a nationwide nutrition care provider.

The current recommended dietary allowance (RDA) for protein is 0.36 grams per pound (or 0.8 grams per kilogram) of body weight per day for adults. For example, a 175-pound person with an average physical activity level should aim to consume about 70 grams of protein per day. Or looking at it from a caloric standpoint, you should consume about 10%-35% of your calories as protein, which equates to 50 to 175 grams a day on a 2,000 calorie diet.

However, Kesmodel points out there’s no assigned gram amount per day for everyone, as our body’s protein needs are highly individualized, based on our body weight, muscle mass, activity level and duration, among other factors. Because of this, protein needs could increase to 1-1.5 grams per kilogram of body weight per day for those with rigorous physical activity or building muscle mass.

And others in the medical community push that recommendation even higher. Dr. Peter Attia, author of New York Times Bestseller, Outlive: The Science & Art of Longevity, stated in his podcast that most people are not getting enough protein. He continued, saying that the current RDA of 0.8 grams per kilogram of body weight is a “pathetic” amount and should be revised to 1 gram per pound of body weight.

But estimating this higher level of protein consumption is where things get murky because, as it turns out, several larger-scale, peer-reviewed studies reveal that consuming too much protein can have some pretty significant downsides.

Protein’s effect on the body

Despite protein’s necessity in our diet, myriad health risks may occur when consuming too much. Kesmodel highlighted some of the ways consuming too much protein may affect various organs and functions of our body.

Kidney & liver function

Our kidneys play a crucial role in processing or filtering the waste products from protein metabolism. When you consume excessive amounts of protein, we’re essentially making our kidneys work overtime. For those with existing kidney issues, this can quickly become a dire situation.

Separately, long-term protein supplementation has been associated with elevated levels of liver toxicity, apoptotic signals, and inflammation in some studies. But not all medical experts agree with this level of concern. Dr. Attia thinks that most people will never reach these concerning levels of protein, requiring most individuals to consume 3 to 4 grams of protein per kilogram of body weight.

Heart health

While protein itself isn’t necessarily bad for your cardiovascular system, the problem often lies in the source of protein. High-protein diets that rely heavily on saturated fats, like red meat, cheeses, and processed meats, may increase your intake of saturated fats, which are known risk factors for heart disease.

Cancer risk

Some studies have suggested that high consumption of red and processed meats may increase the risk of certain types of cancer, particularly colorectal cancer. Colorectal cancer, previously considered a threat to those over the age of 60, is now the leading cause of cancer death among adults under 50.

Weight gain

Surprisingly, excessive protein intake can hinder weight loss efforts.

While protein can help you feel full and satisfied, consuming more protein than your body needs doesn’t magically become muscle…some of the excess protein is stored as fat, if it’s not excreted as waste or broken down for energy.

Furthermore, be mindful of how you’re consuming protein. If you opt for highly-processed, shelf-stable protein bars and shakes, you’ll have less room in your diet for the fresh foods critical for long-term health: veggies and fruits.

Toxin exposure

Registered dietitian Kathy McManus, director of the Department of Nutrition at Harvard’s Brigham and Women’s Hospital, stated that many protein powders contain heavy metals, like lead, arsenic, cadmium, and mercury. A study reported in the journal Toxicology Reports found similar results, as well as additional contaminants linked to cancer and health conditions.

Type 2 diabetes risk

Excessive intake of whey protein may influence the onset of Type 2 diabetes through several physiological mechanisms, including insulin resistance due to high levels of branched-chain amino acids (BCAAs), including leucine.

Other findings

Recent research from the University of Missouri School of Medicine and the University of Pittsburgh found that consuming too much protein (e.g., 100 grams in a 2,000-calorie diet) may trigger cardiovascular and metabolic health issues.

Though these findings may be concerning, the study only had 23 human participants, and the results incorporated mice and cell studies. It should be further replicated with a higher sample size before reconsidering limitations, especially when revising nutritional guidelines.

What can we do to eat healthier?

So, what’s the takeaway here? Protein is still an essential nutrient, and getting enough is crucial for our health. As with most things in nutrition, the key is balance.

So we asked Jamie for some insightful tips to help us strike that protein sweet spot:

Focus on quality, not quantity

Choose whole foods when you can. Lean meats, fish, eggs, legumes, low-fat dairy, and plant-based proteins like nuts and seeds not only provide protein but also pack other beneficial nutrients.

Spread your protein intake throughout the day

Instead of loading up on protein at one meal, try to include a moderate amount at each meal. This can help with better absorption and utilization of the protein.

Don’t forget about other nutrients

A balanced diet includes carbohydrates and healthy fats, which provide an abundance of essential vitamins, minerals, and other micronutrients. Don’t let your protein obsession crowd out nutrient-dense foods, like avocadoes, leafy greens, berries, and olive oil.

Listen to your body

If you’re experiencing digestive issues, feeling overly full, or noticing other unusual symptoms after increasing your protein intake, it might be time to dial it back a bit.

Consider your individual needs

The human body is incredibly complex, and factors like overall diet, exercise habits, genetics, and individual health status all affect how we process nutrients.

Athletes, pregnant women, and older adults need more protein than the average person. Conversely, people with certain health conditions might need to limit their protein intake.

Be wary of protein supplements

There’s no doubt about it: protein powders are convenient.

However, these protein powders, bars and other products are highly processed.

And most contain added sugars, artificial ingredients, and other less savory additives that may conflict with your overall health goals.

At D2D, we like single-ingredient protein supplements, like pea or whey protein.

Keep an eye on your overall calorie intake

Remember, excess protein doesn’t magically turn into muscle—it can contribute to weight gain if you consume more calories than you burn.

Do your research

Nutrition science is complex and constantly evolving. What we know today might be different from what we’ll discover tomorrow. That’s why it’s always a good idea to stay informed, but also verify dramatic diet claims. And always speak with your doctor to ensure that you are on the right protein track.

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Glycemic Index vs. Glycemic Load

glycemic index wordcloud

Monitoring your blood sugar levels is an excellent way to optimize your health and well-being. However, some of these metrics are challenging to understand. But by considering the glycemic index and glycemic load, you get a clearer picture of how a typical serving of food will affect your blood sugar levels.

When your body processes glucose, your insulin levels increase to help deliver glucose to your cells, bringing your blood sugar back to normal. If there’s too much glucose, your pancreas produces more insulin, which then converts the excess sugar into fat for storage. Calculating our glycemic index is a helpful way to begin to understand sugar’s effect on our body.

Glycemic Index

The glycemic index (GI) helps us understand how different foods affect our blood sugar levels. It measures how 50 grams of carbs from a specific food can raise your blood sugar. Foods with higher GI scores (from 1 to 100) cause your blood sugar to spike quickly, which is something you want to avoid. Consistent blood sugar levels are better for your overall health. While your brain and body need glucose to function, getting too much too quickly isn’t good for you.

To keep your blood sugar levels steady, focus on eating more low GI foods, which score between 0 and 55 on the glycemic index. Examples include nuts, most vegetables, whole oats, and certain fruits.

You can also enjoy medium GI foods, scoring between 56 and 70, like rice, whole wheat bread, and most fruits. High GI foods, scoring over 71, such as white bread and potatoes, should be eaten sparingly since they can cause rapid blood sugar spikes.

Eating foods that quickly raise your blood sugar levels can lead to more fat storage in your body. The glycemic index helps you choose foods that promote steady blood sugar levels and healthier eating habits.

Glycemic Load

While the GI measures how quickly 50 grams of carbohydrates from a food can raise your blood sugar, the GL goes further by considering the actual amount of carbohydrates in a typical serving of that food.

The GL is calculated by taking the food’s GI, multiplying it by the carbohydrate content (in grams), and then dividing by 100. For a comprehensive list of foods glycemic index values and their glycemic loads, we recommend you refer to the Harvard Medical School Index.

For example:
  1. Identify the Glycemic Index (GI) of the food, as indicated on a GI chart like this one:
    • For watermelon, the GI is 72.
  2. Determine the amount of carbohydrates in a typical serving:
    • One cup of watermelon (154 grams) contains about 11.6 grams of carbohydrates.
  3. Use the formula to calculate the Glycemic Load (GL):
    • The formula is: GL = (GI × Carbohydrate content per serving) / 100
    • For watermelon: GL=(72×11.6 grams) / 100
    • The glycemic load of one cup of watermelon is 8.35

The glycemic load is often more reliable than the glycemic index alone. For example, watermelon has a high GI of 72, meaning it can raise blood sugar levels quickly. However, watermelon is mostly water, and a typical serving has a very low carbohydrate content.

Therefore, the GL of a serving of watermelon is only 8.35, which is very low. While watermelon can cause a quick rise in blood sugar, it won’t keep levels elevated for long due to its low carbohydrate content.

The glycemic load more accurately measures how certain foods will impact your blood glucose levels by taking the number of carbohydrates in an average serving into account.

To put it in perspective, the GI measures the effect of a standard 50-gram serving of carbohydrates from a food. Eating 50 grams of carbohydrates from watermelon would be unrealistic for most people. One cup of watermelon (about 154 grams) contains approximately 11.6 grams of carbohydrates. You would need to eat over four cups of watermelon to consume 50 grams of carbohydrates.

Putting the Glycemic Load into practice

Here are a few helpful tips to navigate Glycemic Load targets.

When using the glycemic load as a reference for your food, keep in mind that foods between 10 and 15 on the glycemic load are considered moderate.

These moderate GL foods will not keep your blood glucose levels elevated for long periods of time.

However, foods with a glycemic load higher than 15 should be eaten sporadically, as they will spike blood sugar levels and keep them elevated for longer.

Having rapid spikes and consequential decreases will then will cause you to feel unsatiated and fatigued, so be sure to eat these items with protein to even out the spike.

A word of caution: while understanding the glycemic load is important, every person reacts differently to foods, even among very healthy people. For instance, you — an active, individual who eats lots of fresh produce — might have a glucose spike from a cup of watermelon, but your more sedentary friend may not.

The more your glucose levels spike, the higher your chances are of chronic inflammation. The best way to see how your body reacts is to wear a glucose monitor. If you or your members of your family have health-related issues involving blood sugars, talk to your doctor to see if glucose monitoring is appropriate for you.

How is fructose involved?

If you’re wondering how fructose fits into this index, we hear you! It can be hard to talk about glucose without mentioning fructose—take a look at our sugar article.

Unlike glucose, fructose is considered to be a low GI food. With a glycemic index of 19, fructose causes significantly less insulin secretion than glucose. Naturally-occurring fructose is actually ranked lowest on the GI scale of all natural sugars.

High levels of fructose in your body, however, can cause cellular damage— in fact, excess fructose in your body causes seven times more cell damage than excess glucose. This is another reason why you have to be careful when judging foods solely by their glycemic index.

How can I quickly calculate glycemic loads at the grocery store?

Finding the glycemic index (GI) of foods while shopping at the grocery store can be a bit challenging, as GI values are not typically listed on food packaging. However, there are several strategies you can use to access this information:

  • Smartphone Apps: There are many apps available that provide GI values for various foods. Apps like “MyFitnessPal,” “Glycemic Index Load,” and “Fooducate” can be very helpful.

  • Printed Guides and Books: Some people find it useful to carry a small printed guide or book that lists the GI values of common foods. There are several comprehensive guides available in bookstores or online.

  • Online Databases: Before going to the store, you can look up the GI values of foods on websites such as the Glycemic Index Foundation (glycemicindex.com) or other nutrition-focused sites, like Dirt to Dinner in the infographic above!

  • Nutrition Labels: While the GI value might not be listed, you can get a sense of a food’s impact on blood sugar by checking the carbohydrate content and the presence of sugars and dietary fiber. Foods high in fiber and low in sugars generally have a lower GI.

  • Healthy Eating Lists: You can refer to general lists of low GI foods, such as whole grains, legumes, most vegetables, nuts, and certain fruits. These lists can guide your shopping choices.

By using these resources, you can make more informed decisions about the GI of foods and better manage your blood sugar levels.